Hyperbaric oxygen therapy increases telomere length and reduces immunosensitivity in isolated blood cells – a prospective study

Hyperbaric oxygen therapy increases telomere length and reduces immunosensitivity in isolated blood cells – a prospective study

Publication: Aging (Albany NY), peer-reviewed
Study Design: Prospective, controlled study
Participants: 35 healthy adults, average age: 64 years
Location: Sagol Center for Hyperbaric Medicine and Research, Israel

🔍What was observed?

This study demonstrates once again that HBOT has profound effects on cellular aging – this time measured in isolated blood cells, using particularly precise molecular biology methods.

After 60 HBOT sessions (each 90 minutes, 5 times per week, 2 ATA), it was found:


  • Telomere length increased by up to 38% (especially in T cells)

  • Old, senescent immune cells (CD28–CD8+) decreased by up to 37%

  • No medication – pure oxygen therapy with ambient pressure

✨ Highlights & Special Mentions

"HBOT is the first non-pharmacological intervention that has been shown to significantly demonstrate both telomere elongation and reduction in senescence."

✅ Significant rejuvenation of the cellular immune profile
✅ qPCR-based telomere analysis
✅ Improved immune function through reduced senescence
✅ Confirmation of results from the original 2020 telomere study

📌 Good to know

  • The study utilized modern cell separation & qPCR analysis to specifically evaluate certain cell types (e.g., CD4+, CD8+)

  • Telomeres are considered one of the most important biomarkers for biological aging

  • HBOT generates so-called intermittent hyperoxic stimuli that activate the body's own repair mechanisms

"The observed effects suggest a genuine cellular rejuvenation, accompanied by improved immune function."

📈 Conclusion

This study provides another strong argument that HBOT is far more than a symptomatic therapy. It deeply intervenes in cell biology – and, according to data, can partially reverse immune aging.

What was observed?

Highlights & Callouts

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Conclusion

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