Authors: Dr. Shai Efrati et al., Sagol Center for Hyperbaric Medicine and Research (Israel)
Publication: Scientific Reports, Nature Portfolio
Study Design: Randomized, controlled double-blind study
Participants: 73 patients with 'Post-COVID Brain Fog'
🔍What was observed?
This study shows that Hyperbaric Oxygen Therapy (HBOT) can significantly improve cognitive impairments that persist after a COVID-19 illness ('Brain Fog').
🔬 The participants suffered from symptoms such as concentration issues, memory problems, and mental fatigue – even months after the infection.
🧪 After 40 HBOT sessions over 8 weeks, measurable improvements were observed in:
Attention
Working memory
Processing speed
Energy and vitality
✨ Features & Highlights
"The patients showed significant neurocognitive improvements – particularly in the brain's dorsal attention network."
✅ 40 sessions of 90 minutes each, 5 times a week
✅ Pressure chamber with 2 ATA, 100% oxygen
✅ Control group with placebo protocol
✅ Improvements objectively verifiable in fMRI imaging test
📌 Good to know
The study is one of the first double-blind controlled studies that explores HBOT in the context of long COVID symptoms.
Neuronal changes in the brain were also observed – not just subjective reports.
The effects lasted for months after the end of the therapy.
Participants had previously no success with conventional treatments.
"HBOT could be established as an effective therapy for patients with persistent cognitive symptoms following COVID-19."
📈 Conclusion
This study impressively demonstrates that HBOT provides much more than just oxygen supply: it specifically activates regenerative processes in the brain – and thus offers new hope for millions of people with Long COVID symptoms such as brain fog or concentration disorders.
Study (PDF)
Study (PDF)
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